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51.
Pathogenesis of coronary artery disease (CAD) is multi-factorial and several conventional risk factors have been ascribed; LDL-C being one of the important risk factor. However Indian population studies with established CAD often show LDL levels within normal range in patients with proven CAD. We hypothesized that Small dense low density lipoprotein (sdLDL) being more atherogenic might correlate more strongly to the occurrence and severity of CAD. The aim of the study was to evaluate the association between serum small dense LDL level and angiographically documented coronary artery disease. This is a cross sectional case control study in which sdLDL were measured in 126 patients with CAD and in 64 patients without CAD. Total cholesterol, HDL Cholesterol, LDL cholesterol and triglycerides were measured by standard methods along with other traditional risk factors. Direct quantitative measurement of sdLDL was done by enzymatic analysis. Mean sdLDL level was higher in patients with coronary stenosis than patients without coronary stenosis (16.3 ± 6.8 vs. 10.1 ± 5.7 mg/dL respectively, (p < 0.001). There was significant correlation between mean sdLDL and severity of CAD as assessed by syntax score with mean sdLDL level in low, intermediate and high syntax score being 15.0 ± 5.8, 20.1 ± 6.7 and 22.7 ± 7.3 mg/dL respectively (p value <0.001). A cut off value of 10.02 mg/dL was associated with presence of CAD (95 % CI 0.82–0.93, p < 0.001) using ROC curve. In conclusion Indian patients with established CAD have higher sdLDL levels compared to individuals without CAD despite having comparable LDL levels.  相似文献   
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Can dams and reservoirs cause earthquakes?   总被引:1,自引:0,他引:1  
No! Not on their own. But, stresses and pore pressure due to natural causes may already have accumulated in crustal rocks at some dam sites to near critical levels for fresh faulting or renewed slip on nearby pre-existing faults. The stresses and pore pressure induced by impoundment of reservoirs there may marginally abet the tendencies to such failures and even trigger or induce earthquakes by being the proverbial last straw.  相似文献   
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The history of Early Childhood Education in India dates from the 1890s, though growth remained restricted till independence. In 1953, the Government began to play a larger role, promoting through voluntary effort, kindergartens (balwadis) in rural areas. The first large training effort was the Bal Sevika (child care worker) scheme launched in 1969 by the Indian Council of Child Welfare.

The second big breakthrough came with the Integrated Child Development Services in 1974, the world's largest intervention aimed at the most vulnerable children in urban slums, rural areas and tribal communities. Presently over 10 million children aged 0–6 years receive a package of six services in 400,000 centres, throughout the country.

There are also a number of small‐scale innovative programmes which reflect not only the geographic, cultural and occupational diversity of the country, but also represent a diversity of auspices ‐‐‐ from statutory provision in industrial units to community‐based initiatives, educational institutions, charitable trusts, women's organisations, trade unions, denominational groups, commercial ventures and nonprofit organisations, as well as variety in the nature and quality of services offered.

While the ICDS is characterised by its vast outreach, explicit targetting and integrated approach with emphasis on child survival and health, the small innovative programmes are known for flexibility, sensitivity and responsiveness to local need, emphasis on quality, cultural relevance and low‐cost approaches, experimentation in programme content and a strong component of community participation.  相似文献   

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ABSTRACT

The aim of this study is to determine primary school administrators’ and teachers’ opinions about the quality of their schools; the school administrators and teachers’ knowledge about Total Quality Management and quality tools and the quality tools used in primary schools. The research has been carried out with a qualitative approach and it is in the case study pattern. The participants consisted of 16 teachers and 4 school administrators working in primary schools in North Cyprus. The participants were chosen via maximum sampling method. The findings show that the current situation in schools contradicts with the basic principles of Total Quality Management. It was determined that school administrators were ignorant about Total Quality Management and none of the teachers and school administrators had previously heard the concept of quality tools. Teachers and school administrators mentioned disabled students as an issue. It seems like teachers have problems in behaving in the right way towards these students. They do not know how to improve these students’ talents because they are not educated on the subject. Via tools of quality teachers and school administrators may find reasons and solutions for issues like people with disabilities and plan events to promote disability awareness.  相似文献   
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When tests are designed to measure dimensionally complex material, DIF analysis with matching based on the total test score may be inappropriate. Previous research has demonstrated that matching can be improved by using multiple internal or both internal and external measures to more completely account for the latent ability space. The present article extends this line of research by examining the potential to improve matching by conditioning simultaneously on test score and a categorical variable representing the educational background of the examinees. The responses of male and female examinees from a test of medical competence were analyzed using a logistic regression procedure. Results show a substantial reduction in the number of items identified as displaying significant DIF when conditioning is based on total test score and a variable representing educational background as opposed to total test score only.  相似文献   
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Most plants are attached via their roots to specialized fungi. The filamentous hyphae of these fungi extend beyond the nutrient-depleted zone in the soil, absorbing and supplying nutrients to the plants in exchange for photosynthetically-made carbon compounds manufactured by the plant. The hyphae also attach to litter and decompose the organic matter, releasing the mineral ions sequestered in the structural polymers. The mineral ions are absorbed and translocated to the roots. Most plants are so dependent on their fungal partners for supplying nutrients that they languish or die without them. Our understanding of this fascinating interaction, to a large extent, has come from the pioneering work of Sir David J Read, FRS, Emeritus Professor of Plant Sciences at the University of Sheffield, UK. Ramesh Maheshwari is a former Professor and Chairman of the Department of Biochemistry, Indian Institute of Science, Banglaore. This is his sixth article for Resonance.  相似文献   
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Informative, useful, and with practical inputs on quality assurance and accreditation in open, distance and e‐learning education, this book is worthy to be consulted by teachers, researchers, quality technicians, practitioners, and policy makers. If the content of this book is likely to be relevant to you, you should arrange to borrow a copy for a while. Ramesh Sharma  相似文献   
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